The problems presented by food safety regulations underpinned by inadequate science are not limited to developing countries, a common misperception. A troubling number of developed countries have instituted food safety regulations that also use outdated or inaccurate data as their evidence base. The Global Harmonization Initiative (GHI), the only impartial, independent and international organisation working to harmonise science-based food safety regulations, is dedicated to bringing together scientists, policymakers, regulators and industry subject matter experts at this new forum to advance the use of modern, validated scientific solutions as the basis for updating food safety regulations around the world.